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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 12.42
Human Site: T1181 Identified Species: 18.22
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 T1181 E Q V L S K K T P P A P S P F
Chimpanzee Pan troglodytes XP_518055 1227 139177 T1176 E Q V L S K K T A P A P S P F
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 T1183 E Q V P S K K T P P A P S L F
Dog Lupus familis XP_549061 1234 139874 T1183 E Q V L L K K T T P A A S S F
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 P1181 D Q V Q L K Q P M F V S S S D
Rat Rattus norvegicus Q7M6Z5 1394 158861 P1336 T Q S Q S P P P P Q L Q P V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 G1173 L K D I T D Q G V F M K K P S
Frog Xenopus laevis Q91784 1226 138905 L1177 G Q V L S I K L Q R K P S T A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 A1306 E E L R Q R A A C E L P N N R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 S735 A G V A V G S S I P N V R N I
Honey Bee Apis mellifera XP_395595 1064 123475 L1015 K K N L N R T L F V E N I E E
Nematode Worm Caenorhab. elegans P46873 699 78760 D650 V I N K Y K S D Q K L S T S K
Sea Urchin Strong. purpuratus P46872 699 78679 V650 G E A D L S N V F L T Y N L E
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 L997 G Q L S M R K L A V V G Q G G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 W986 G K Q G G R L W R W K R S H H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 G879 L G T D A G L G G F S I G S R
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 93.3 86.6 73.3 N.A. 26.6 20 N.A. N.A. 6.6 46.6 13.3 N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 93.3 86.6 73.3 N.A. 40 20 N.A. N.A. 33.3 46.6 40 N.A. 20 33.3 13.3 13.3
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 7 0 7 7 13 0 25 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 7 0 7 13 0 7 0 7 0 0 0 0 0 0 7 % D
% Glu: 32 13 0 0 0 0 0 0 0 7 7 0 0 7 13 % E
% Phe: 0 0 0 0 0 0 0 0 13 19 0 0 0 0 25 % F
% Gly: 25 13 0 7 7 13 0 13 7 0 0 7 7 7 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 7 0 7 0 7 0 0 7 0 0 7 7 0 7 % I
% Lys: 7 19 0 7 0 38 38 0 0 7 13 7 7 0 7 % K
% Leu: 13 0 13 32 19 0 13 19 0 7 19 0 0 13 0 % L
% Met: 0 0 0 0 7 0 0 0 7 0 7 0 0 0 0 % M
% Asn: 0 0 13 0 7 0 7 0 0 0 7 7 13 13 0 % N
% Pro: 0 0 0 7 0 7 7 13 19 32 0 32 7 19 0 % P
% Gln: 0 50 7 13 7 0 13 0 13 7 0 7 7 0 0 % Q
% Arg: 0 0 0 7 0 25 0 0 7 7 0 7 7 0 19 % R
% Ser: 0 0 7 7 32 7 13 7 0 0 7 13 44 25 7 % S
% Thr: 7 0 7 0 7 0 7 25 7 0 7 0 7 7 0 % T
% Val: 7 0 44 0 7 0 0 7 7 13 13 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _